Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice. Crews L, Mizuno H, Desplats P, Rockenstein E, Adame A, Patrick C, Winner B, Winkler J, Masliah E. J Neurosci. 2008 Apr 16;28(16):4250-60. PMID: 18417705

Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington’s disease. Desplats PA, Lambert JR, Thomas EA. Neurobiol Dis. 2008 Sep;31(3):298-308. PMID: 18595722

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington’s disease transgenic mice. Thomas EA, Coppola G, Desplats PA, Tang B, Soragni E, Burnett R, Gao F, Fitzgerald KM, Borok JF, Herman D, Geschwind DH, Gottesfeld JM. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15564-9. PMID: 18829438