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2008

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  3. 2008
  • By pendari1060
  • August 19, 2021
  • 0

Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice. Crews L, Mizuno H, Desplats P, Rockenstein E, Adame A, Patrick C, Winner B, Winkler J, Masliah E. J Neurosci. 2008 Apr 16;28(16):4250-60. PMID: 18417705

Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice. Crews L, Mizuno H, Desplats P, Rockenstein E, Adame A, Patrick C, Winner B, Winkler J, Masliah E. J Neurosci. 2008 Apr 16;28(16):4250-60. PMID: 18417705
  • By pendari1060
  • August 19, 2021
  • 0

Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington’s disease. Desplats PA, Lambert JR, Thomas EA. Neurobiol Dis. 2008 Sep;31(3):298-308. PMID: 18595722

Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington’s disease. Desplats PA, Lambert JR, Thomas EA. Neurobiol Dis. 2008 Sep;31(3):298-308. PMID: 18595722
  • By pendari1060
  • August 19, 2021
  • 0

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington’s disease transgenic mice. Thomas EA, Coppola G, Desplats PA, Tang B, Soragni E, Burnett R, Gao F, Fitzgerald KM, Borok JF, Herman D, Geschwind DH, Gottesfeld JM. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15564-9. PMID: 18829438

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington’s disease transgenic mice. Thomas EA, Coppola G, Desplats PA, Tang B, Soragni E, Burnett R, Gao F, Fitzgerald KM, Borok JF, Herman D, Geschwind DH, Gottesfeld JM. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15564-9. PMID: 18829438
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Research in our lab is aimed at elucidating the dynamic mechanisms of DNA methylation, which might contribute to onset and progression of the most prevalent neurodegenerative diseases of the elderly, Parkinson’s and Alzheimer’s.

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