Desplats Lab at UC San Diego
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2016

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  • By pendari1060
  • August 20, 2021
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a-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy body disease. Spencer B, Kim C, Gonzalez T, Bisquertt A, Patrick C, Rockenstein E, Adame A, Lee SJ, Desplats P, Masliah E. Hum Mol Genet. 2016 Mar 15;25(6):1100-15. PMID: 26740557

a-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy body disease. Spencer B, Kim C, Gonzalez T, Bisquertt A, Patrick C, Rockenstein E, Adame A, Lee SJ, Desplats P, Masliah E. Hum Mol Genet. 2016 Mar 15;25(6):1100-15. PMID: 26740557
  • By pendari1060
  • August 20, 2021
  • 0

Reducing Endogenous a-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer’s Disease Transgenic Mouse Model. Spencer B, Desplats PA, Overk CR, Valera-Martin E, Rissman RA, Wu C, Mante M, Adame A, Florio J, Rockenstein E, Masliah E. J Neurosci. 2016 Jul 27;36(30):7971-84. PMID: 27466341

Reducing Endogenous a-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer’s Disease Transgenic Mouse Model. Spencer B, Desplats PA, Overk CR, Valera-Martin E, Rissman RA, Wu C, Mante M, Adame A, Florio J, Rockenstein E, Masliah E. J Neurosci. 2016 Jul 27;36(30):7971-84. PMID: 27466341
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Research in our lab is aimed at elucidating the dynamic mechanisms of DNA methylation, which might contribute to onset and progression of the most prevalent neurodegenerative diseases of the elderly, Parkinson’s and Alzheimer’s.

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UCSD School of Medicine Department of Neurosciences MTF Room 344 9500 Gilman Drive Mail code 0624 La Jolla
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