ESCRT-mediated uptake and degradation of brain-targeted a-synuclein single chain antibody attenuates neuronal degeneration in vivo. Spencer B, Emadi S, Desplats P, Eleuteri S, Michael S, Kosberg K, Shen J, Rockenstein E, Patrick C, Adame A, Gonzalez T, Sierks M, Masliah E. Mol Ther. 2014 Oct;22(10):1753-67. PMID: 25008355